Connecticut Maxillofacial Surgeons, llc

“Three-Dimensional Ridge Augmentation with Xenograft and Recombinant Human Platelet-Derived Growth Factor-BB in Humans: Report of Two Cases”

by Massimo Simion, MD, DDS, Isabella Rocchietta, DDS, & Claudia Dellavia, DDS

A paper presenting two patients who underwent three-dimensional ridge augmentation using a xenograft in combination with recombinant human platelet-derived growth factor-BB (rhPDGF-BB).  The report suggests that the use of rhPDGF-BB in combination with a deproteinized bovine graft may have the potential to regenerated large three-dimensional alveolar defects in humans.

The article renders very nice photo and radiographich images of the post-treatment ridge forms and demonstrates, at least on two patients with limited follow-up, that vertical ridge augmentation in the mandibular arch may be possible under these special conditions.

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